| 论文题目： | The locust genome provides insight into swarm formation and long-distance flight |
| 论文题目英文： | |
| 作者： | 王宪辉，#X. Fang，杨鹏程，#X. Jiang，姜枫，赵德健，李播雷，崔峰，魏佳宁，马川，王云丹，何静，罗媛，王志峰，郭晓姣，郭伟， X. Wang， Y. Zhang， M. Yang，郝树广，陈兵，马宗源，于丹， #Z. Xiong， #Y. Zhu， #D. Fan， #L. Han， #B. Wang， #Y. Chen， #J. Wang， #L. Yang， #W. Zhao， #Y. Feng， #G. Chen，#J. Lian， #Q. Li，#Z. Huang， #X. Yao， #N. Lv，#G. Zhang，#Y. Li，#J. Wang，#王俊， #B. Zhu，康乐* |
| 论文出处： | |
| 年： | 2014 |
| 卷： | 5 |
| 期： | 2957 |
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| 联系作者： | 康乐 |
| 发表期刊： | Nature Communications |
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| 论文连接 | http://www.nature.com/ncomms/2014/140114/ncomms3957/abs/ncomms3957.html |
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| 摘要: | Locusts are one of the world’s most destructive agricultural pests and represent a useful model system in entomology. Here we present a draft 6.5 Gb genome sequence of Locusta migratoria, which is the largest animal genome sequenced so far. Our findings indicate that the large genome size of L. migratoria is likely to be because of transposable element proliferation combined with slow rates of loss for these elements. Methylome and transcriptome analyses reveal complex regulatory mechanisms involved in microtubule dynamic-mediated synapse plasticity during phase change. We find significant expansion of gene families associated with energy consumption and detoxification, consistent with long-distance flight capacity and phytophagy. We report hundreds of potential insecticide target genes, including cys-loop ligand-gated ion channels, G-protein-coupled receptors and lethal genes. The L. migratoria genome sequence offers new insights into the biology and sustainable management of this pest species, and will promote its wide use as a model system. |
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