论文
论文题目: Comparative Genomics Reveals Convergent Evolution Between the Bamboo-Eating Giant and Red Pandas
论文题目英文:
作者: 胡义波①,吴琦①,马帅①,马天笑①,单磊,王潇,聂永刚,#Ze-Min Ning,艳丽,#Yun-Fang Xiu,魏辅文*
论文出处:
年: 2017
卷: 114
期: 5
页: 1081-1086
联系作者: 魏辅文
发表期刊: Proceedings of the National Academy of Sciences of the United States of America
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论文连接 http://www.pnas.org/content/114/5/1081.long
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摘要: Phenotypic convergence between distantly related taxa often mirrors adaptation to similar selective pressures and may be driven by genetic convergence. The giant panda (Ailuropoda melanoleuca) and red panda (Ailurus fulgens) belong to different families in the order Carnivora, but both have evolved a specialized bamboo diet and adaptive pseudothumb, representing a classic model of convergent evolution. However, the genetic bases of these morphological and physiological convergences remain unknown. Through de novo sequencing the red panda genome and improving the giant panda genome assembly with added data, we identified genomic signatures of convergent evolution. Limb development genes DYNC2H1and PCNT have undergone adaptive convergence and may be important candidate genes for pseudothumb development. As evolutionary responses to a bamboo diet, adaptive convergence has occurred in genes involved in the digestion and utilization of bamboo nutrients such as essential amino acids, fatty acids, and vitamins. Similarly, the umami taste receptor gene TAS1R1 has been pseudogenized in both pandas. These findings offer insights into genetic convergence mechanisms underlying phenotypic convergence and adaptation to a specialized bamboo diet.
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