陈金锋，博士，研究员，博士生导师；中国科学院动物研究所有害生物与宿主互作基因组学研究组组长。 2004年毕业于西北农林科技大学，2006年于西北农林科技大学获得生物化学与分子生物学硕士学位，2012年于中国科学院遗传与发育生物学研究所获得遗传学博士学位。2013-2019期间在加州大学河滨分校进行博士后研究，并于2017年6月起任助理项目科学家(Assistant Project Scientist)。2019-2020期间在希望之城国家医疗中心(City of Hope National Medical Center)担任职员科学家(Staff Scientist)。2020年10月起任中国科学院动物研究所农业虫害鼠害综合治理研究国家重点实验室研究组组长。

　　主要从事基因组学研究，解析复杂基因组的结构及进化规律，揭示基因组中重复序列的结构、调控机制及功能。研究成果发表于Nature Genetics, Cell Host & Microbe, Nature Communications，Proc Natl Acad Sci U S A等刊物。担任Proc Natl Acad Sci U S A，Genome Biology，Insect Science等10余种刊物审稿人。

　　研究组以作物与病原、害虫互作为主线，利用基因组学大数据分析，整合第三代测序、单细胞测序等多组学技术，研究基因组结构与进化，重要发育过程的细胞谱系及基因调控，宿主与病原互作等科学问题，探索开发可持续绿色病虫害防控方法，为我国主要作物优质高产提供技术平台和理论依据。

（* 共同第一作者）：

1. Chen J*^#, Liu Y*, Liu M*, Guo W*, Wang Y*, He Q*, Chen W, Liao Y, Zhang W, Gao Y, Dong K, Ren R, Yang T, Zhang L, Qi M, Li Z, Zhao M, Wang H, Wang J, Qiao Z, Li H, Jiang Y, Liu G, Song X, Deng Y, Li H, Yan F, Dong Y, Li Q, Li T, Yang W, Cui J, Wang H, Zhou Y, Zhang X, Jia G, Lu P, Zhi H, Tang S^#, Diao X^#. Pangenome analysis reveals genomic variations associated with domestication traits in broomcorn millet. Nature Genetics. 2023; 55:2243-2254.
2. He Q*, Tang S*, Zhi H*, Chen J*, Zhang J, Liang H, Alam O, Li H, Zhang H, Xing L, Li X, Zhang W, Wang H, Shi J, Du H, Wu H, Wang L, Yang P, Xing L, Yan H, Song Z, Liu J, Wang H, Tian X, Qiao Z, Feng G, Guo R, Zhu W, Ren Y, Hao H, Li M, Zhang A, Guo E, Yan F, Li Q, Liu Y, Tian B, Zhao X, Jia R, Feng B, Zhang J, Wei J, Lai J, Jia G^#, Purugganan M^#, Diao X^#. A graph-based genome and pangenome variation of the model plant Setaria. Nature Genetics 2023; 55:1232-1242.
3. Sun Y, Liu Y, Shi J, Wang L, Liang C, Yang J, Chen J^#, Chen M^#. Biased mutations and gene losses underlying diploidization of the tetraploid broomcorn millet genome. Plant J. 2023; 113:787-801.
4. Liu N*, Xu Z*, Li Q*, Cao Y, Yang D, Liu S, Wang X, Mi Y, Liu Y, Ding C, Liu Y, Li Y, Yuan Y, Gao G, Chen J^#, Qian W^#, Zhang X^#. A lncRNA fine-tunes salicylic acid biosynthesis to balance plant immunity and growth. Cell Host & Microbe. 2022; 30:1124–38.
5. Liu Y, Rao J, Mi Y, Chen L, Feng L, Li Q, Geng J, Yang X, Zhan X, Ren L^#, Chen J^#, Zhang X^#. SARS-CoV-2 RNAs are processed into 22-nt vsRNAs in Vero cells. Front Immunol. 2022; 13:1008084.
6. Griffiths, J.I.*, Chen, J.*, Cosgrove, P.A., O’Dea, A., Sharma, P., Ma, C., Trivedi, M., Kalinsky, K., Wisinski, K.B., O’Regan, R., Makhoul, I., Spring, L.M., Bardia, A., Adler, F.R., Cohen, A.L., Chang, J.T., Khan, Q.J. & Bild, A.H. Serial single-cell genomics reveals convergent subclonal evolution of resistance as patients with early-stage breast cancer progress on endocrine plus CDK4/6 therapy. Nature Cancer. 2021; 2:658-671
7. Chen J*, Lu L*, Robb SMC, Collin M, Okumoto Y, Stajich JE, Wessler SR. Genomic diversity generated by a transposable element burst in a rice recombinant inbred population. Proc Natl Acad Sci U S A. 2020; 117:26288-26297.
8. Chen J, Lu L, Benjamin J, Diaz S, Hancock CN, Stajich JE, et al. Tracking the origin of two genetic components associated with transposable element bursts in domesticated rice. Nature communications. 2019; 10:641.
9. Liao Y, Zhang X, Li B, Liu T, Chen J, Bai Z, Wang M, Shi J, Walling JG, Wing RA, Jiang J, Chen M. Comparison of Oryza sativa and Oryza brachyantha Genomes Reveals Selection-Driven Gene Escape from the Centromeric Regions. Plant Cell. 2018; 30:1729-1744.
10. Ou S, Chen J, Jiang N. Assessing genome assembly quality using the LTR Assembly Index (LAI). Nucleic Acids Res. 2018; 46:e126.
11. Lu L*, Chen J*, Robb SMC, Okumoto Y, Stajich JE, Wessler SR. Tracking the genome-wide outcomes of a transposable element burst over decades of amplification. Proc Natl Acad Sci U S A. 2017; 114:E10550–E9.
12. Chen J*, Huang Q*, Gao D*, Wang J*, Lang Y*, Liu T, et al. Whole-genome sequencing of Oryza brachyantha reveals mechanisms underlying Oryza genome evolution. Nature communications. 2013; 4:1595.
13. Lu F, Ammiraju JS, Sanyal A, Zhang S, Song R, Chen J, et al. Comparative sequence analysis of MONOCULM1-orthologous regions in 14 Oryza genomes. Proc Natl Acad Sci U S A. 2009; 106:2071-6.