翟晶磊 博士 中国科学院动物研究所副研究员。

工作经历：

　　2020年-2023年 中国科学院动物研究所 博士后 特别研究助理

　　长期从事哺乳动物早期胚胎发育相关研究，主要研究方向有：利用生物材料构建啮齿类和灵长类胚胎体外长时程培养体系、利用胚胎培养体系研究灵长类动物原肠运动与早期器官发育核心事件、构建灵长类早期胚胎和胚外组织单细胞多组学图谱等。相关研究不仅为发育生物学和再生医学等领域奠定理论基础，更为揭示人类出生缺陷等不良妊娠结局提供数据支持。以第一和共同第一作者在Science (2019), Nature (2022), Cell (2023), Developmental Cell (2023), Advanced Science (2022)等顶级学术期刊。主持国家自然科学基金-青年项目，中国科学院特别研究助理资助项目，参与中国科学院先导课题、国家重点研发计划等多个重要项目。

　　（#第一作者或共同第一作者；*通讯作者）

1. Zhai, J.#, Xu, Y.#, Wan, H.#, Yan, R.#, Guo, J.#, Skory, R.#, Yan, L., Wu, X., Sun, F., Chen, G., Zhao, W., Yu, K., Li, W., Guo, F.*, Plachta, N.*, and Wang, H.* (2023). Neurulation of the cynomolgus monkey embryo achieved from 3D blastocyst culture. Cell 186, 2078-2091 e2018.（期刊论文）
2. Jiang, X.#, Zhai, J.#, Xiao, Z.#, Wu, X.#, Zhang, D.#, Wan, H., Xu, Y., Qi, L., Wang, M., Yu, D., Liu, Y., Wu, H., Sun, R., Xia, S., Yu, K., Guo, J., and Wang, H. (2023). Identifying a dynamic transcriptomic landscape of the cynomolgus macaque placenta during pregnancy at single-cell resolution. Dev Cell.（期刊论文）
3. Yan, R.#, Cheng, X.#, Gu, C.#, Xu, Y.#, Long, X.#, Zhai, J., Sun, F., Qian, J., Du, Y., Wang, H., and Guo, F. (2023). Dynamics of DNA hydroxymethylation and methylation during mouse embryonic and germline development. Nat Genet 55, 130-143.（期刊论文）
4. Zhai, J.#, Guo, J.#, Wan, H.#, Qi, L.#, Liu, L.#, Xiao, Z., Yan, L., Schmitz, D.A., Xu, Y., Yu, D., Wu, X., Zhao, W., Yu, K., Jiang, X., Guo, F.*, Wu, J.*, and Wang, H.* (2022). Primate gastrulation and early organogenesis at single-cell resolution. Nature 612, 732-738.（期刊论文）
5. Gu, Z.#, Guo, J.#, Zhai, J.#, Feng, G.#, Wang, X., Gao, Z., Li, K., Ji, S., Wang, L., Xu, Y., Chen, X., Wang, Y., Guo, S., Yang, M., Li, L., Han, H., Jiang, L., Wen, Y., Wang, L., Hao, J., Li, W., Wang, S.*, Wang, H.*, and Gu, Q.* (2022). A Uterus-Inspired Niche Drives Blastocyst Development to the Early Organogenesis. Adv Sci (Weinh) 9, e2202282.（期刊论文）
6. Zhai, J.#, Xiao, Z.#, Wang, Y.#, and Wang, H.* (2022). Human embryonic development: from peri-implantation to gastrulation. Trends Cell Biol 32, 18-29.（特邀综述）
7. Ma, H.#, Zhai, J.#, Wan, H.#, Jiang, X.#, Wang, X., Wang, L., Xiang, Y., He, X., Zhao, Z.A., Zhao, B., Zheng, P.*, Li, L.*, and Wang, H.* (2019). In vitro culture of cynomolgus monkey embryos beyond early gastrulation. Science 366, 738. （期刊论文）
8. Jia, Y.#, Cao, N., Zhai, J., Zeng, Q., Zheng, P., Su, R., Liao, T., Liu, J., Pei, H., Fan, Z., Zhou, J., Xi, J., He, L., Chen, L., Nan, X., Yue, W., and Pei, X. (2020). HGF Mediates Clinical-Grade Human Umbilical Cord-Derived Mesenchymal Stem Cells Improved Functional Recovery in a Senescence-Accelerated Mouse Model of Alzheimer's Disease. Adv Sci (Weinh) 7, 1903809. （期刊论文）
9. Wang, F., Jia, Y., Liu, J., Zhai, J.#, Cao, N., Yue, W., He, H., and Pei, X. (2017). Dental pulp stem cells promote regeneration of damaged neuron cells on the cellular model of Alzheimer's disease. Cell Biol Int 41, 639-650.