姓  名: 刘佩佩
学  科: 再生医学
电话/传真:  / 
电子邮件: liupeipei@ioz.ac.cn
通讯地址: 北京市朝阳区北辰西路1号院5号 中国科学院动物研究所
中国科学院动物研究所干细胞与生殖生物学国家重点实验室 100101
更多信息: 干细胞与神经发育疾病研究组     

简历介绍:

  教育经历:

  (1) 2015-09 至 2018-07, 中国科学院动物研究所, 发育生物学, 博士

  (2) 2011-09 至 2014-07, 厦门大学, 细胞生物学, 硕士

  (3) 2007-09 至 2011-07, 山东师范大学, 生物科学, 学士

  科研与学术工作经历:

  (1) 2018-07 至 今, 中国科学院动物研究所, 干细胞与生殖生物学国家重点实验室, 助理研究员

研究领域:

  以小鼠、人多能干细胞及病人来源的组织或细胞为模型,从事神经发育、神经疾病机制与药物靶点探索的研究,发现新型的相关疾病分子靶标及干预治疗策略

社会任职:

获奖及荣誉:

承担科研项目情况:

代表论著:

(#共同第一作者)

  1. Liu, P.P.#, Lu, S.P.#, Li, X.#, Tang, G.B., Liu, X., Dai, S.K., Jiao, L.F., Lin, X.W., Li, X.G., Hu, B., et al. (2023). Abnormal chromatin remodeling caused by ARID1A deletion leads to malformation of the dentate gyrus. Cell Death Differ 30, 2187-2199. 10.1038/s41418-023-01199-w.
  2. Liu, P.P.#, Dai, S.K.#, Mi, T.W.#, Tang, G.B., Wang, Z., Wang, H., Du, H.Z., Tang, Y., Teng, Z.Q., and Liu, C.M. (2022). Acetate supplementation restores cognitive deficits caused by ARID1A haploinsufficiency in excitatory neurons. EMBO Mol Med 14, e15795. 10.15252/emmm.202215795.
  3. Liu, X., Dai, S.K., Liu, P.P., and Liu, C.M. (2021). Arid1a regulates neural stem/progenitor cell proliferation and differentiation during cortical development. Cell Prolif 54, e13124. 10.1111/cpr.13124.
  4. Dai SK, Liu PP, Du HZ, Liu X, Xu YJ, Liu C, Wang YY, Teng ZQ*, Liu CM*. Histone crotonylation regulates neural stem cell fate decisions by activating bivalent promoters. EMBO Reports 2021, 22 (10): e52023.
  5. Liu PP#, Xu YJ#, Dai SK, Du HZ, Wang YY, Li XG, Teng ZQ, Liu CM#. Polycomb Protein EED Regulates Neuronal Differentiation through Targeting SOX11 in Hippocampal Dentate Gyrus. Stem Cell Reports. 2019 Jul 9;13(1):115-131. doi: 10.1016/j.stemcr.2019.05.010.
  6. Liu C, Dai SK, Sun Z, Wang Z, Liu PP, Du HZ, Yu S*, Liu CM*, Teng ZQ*. GA-binding protein GABPβ1 is required for the proliferation of neural stem/progenitor cells. Stem Cell Res. 2019 Jul 15;39:101501. doi: 10.1016/j.scr.2019.101501.
  7. Xu YJ#, Liu PP#, Ng SC, Teng ZQ, Liu CM*. Regulatory Networks between Polycomb Complexes and Non-coding RNAs in Central Nervous System. J Mol Cell Biol. 2019 Jul 10. pii: mjz058. doi: 10.1093/jmcb/mjz058.)
  8. Duan RS, Liu PP, Xi F, Wang WH, Tang GB, Wang RY*, Saijilafu*, Liu CM*. Wnt3 and Gata4 regulate axon regeneration in adult mouse DRG neurons. Biochem Biophys Res Commun. 2018 May 5;499(2):246-252
  9. Duan RS, Tang GB, Du HZ, Hu YW, Liu PP, Xu YJ, Zeng YQ, Zhang SF, Wang RY, Teng ZQ, Liu CM*. Polycomb protein family member CBX7 regulates intrinsic axon growth and regeneration. Cell Death Differ. 2018 Sep;25(9):1598-1611.
  10. Liu PP#, Xu YJ#, Teng ZQ, Liu CM*. Polycomb Repressive Complex 2: Emerging Roles in the Central Nervous System. Neuroscientist. 2018 Jun;24(3):208-220.
  11. Liu PP, Tang GB, Xu YJ, Zeng YQ, Zhang SF, Du HZ, Teng ZQ*, Liu CM*. MiR-203 Interplays with Polycomb Repressive Complexes to Regulate the Proliferation of Neural Stem/Progenitor Cells. Stem Cell Reports. 2017 Jul 11;9(1):190-202.
  12. Tang GB#, Zeng YQ#, Liu PP#, Mi TW, Zhang SF, Dai SK, Tang QY, Yang L, Xu YJ, Yan HL, Du HZ, Teng ZQ*, Zhou FQ*, Liu CM*. The Histone H3K27 Demethylase UTX Regulates Synaptic Plasticity and Cognitive Behaviors in Mice. Front Mol Neurosci. 2017 Aug 24;10:267.  

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