滕兆乾，博士，研究员，博士生导师，干细胞与脑损伤修复研究组组长。
　　2005年博士毕业于中国科学院动物研究所，先后在中国农业大学、美国新墨西哥大学医学院、路易斯安那州立大学健康科学中心以及约翰·霍普金斯大学医学院做博士后与Research Associate。主要从事神经再生、脑损伤、神经退行性疾病与精神疾病方面的研究，研究成果发表在Nature Neuroscience、Molecular Psychiatry、Cell、Cell Stem Cell、Stem Cell Reports、Glia等国际学术期刊上。

　　研究工作主要集中在脑损伤、神经退行性疾病与精神疾病的致病机理、以及神经再生修复策略的应用研究。研究组的主要研究方向包括：（1）神经再生障碍的细胞与分子机制；（2）小胶质细胞在疾病发生发展过程中表型转化的分子机制；（3）人源功能性小胶质细胞与神经元的定向分化；（4）神经功能重塑的有效途径。

　　目前承担国家重点研发计划项目、中国科学院A类战略性先导科技专项、国家自然科学基金项目、北京市自然科学基金项目等。

1. Wang YY, Deng YS, Dai SK, Mi TW, Li RY, Liu PP, Liu C, He BD, He XC, Du HZ, Yang HC, Tang Y, Liu CM*, Teng ZQ*. Loss of microglial EED impairs synapse density, learning, and memory. Molecular Psychiatry 2022, doi: 10.1038/s41380-022-01576-w.
2. He XC, Wang J, Du HZ, Liu CM*, Teng ZQ*. Intranasal Administration of Agomir-let-7i Improves Cognitive Function in Mice with Traumatic Brain Injury. Cells. 2022, 11(8): 1348.
3. Liu XT, Liu CM*, Teng ZQ*. Mouse model of voluntary movement deficits induced by needlestick injuries to the primary motor cortex. Journal of Neuroscience Methods 2022, 365: 109380.
4. Dai SK, Liu PP, Du HZ, Liu X, Xu YJ, Liu C, Wang YY, Teng ZQ*, Liu CM*. Histone crotonylation regulates neural stem cell fate decisions by activating bivalent promoters. EMBO Reports 2021, 22 (10): e52023.
5. Liu C^#, Dai SK^#, Shi RX, He XC, Wang YY, He BD, Sun XW, Du HZ, Liu CM*, Teng ZQ*. Transcriptional profiling of microglia in the injured brain reveals distinct molecular features underlying neurodegeneration. Glia 2021, 69 (5): 1292-1306.
6. Wang ZM, Liu C, Wang YY, Deng YS, He XC, Du HZ, Liu CM*, Teng ZQ*. SerpinA3N deficiency deteriorates impairments of learning and memory in mice following hippocampal stab injury. Cell Death Discovery 2020, 6 (1): 1-11.
7. Tang QY, Zhang SF, Dai SK, Liu C, Wang YY, Du HZ, Teng ZQ*, Liu CM*. UTX regulates human neural differentiation and dendritic morphology by resolving bivalent promoters. Stem Cell Reports 2020, 15 (2): 439-453.
8. Mi TW, Sun XW, Wang ZM, Wang YY, He XC, Liu C, Zhang SF, Du HZ, Liu CM*, Teng ZQ*. Loss of MicroRNA-137 Impairs the Homeostasis of Potassium in Neurons via KCC2. Experimental Neurobiology 2020, 29(2): 138-149.
9. Liu C^#, Dai SK^#, Sun Z^#, Wang Z, Liu PP, Du HZ, Yu S*, Liu CM*, Teng ZQ*. GA-binding protein GABPβ1 is required for the proliferation of neural stem/progenitor cells. Stem Cell Research 2019, 39: 101501.
10. Yan HL^#, Sun XW^#, Wang ZM^#, Liu PP^#, Mi TW, Liu C, Wang YY, He XC, Du HZ, Liu CM*, Teng ZQ*. MiR-137 Deficiency Causes Anxiety-Like Behaviors in Mice. Frontiers in Molecular Neuroscience 2019, 12: 260.
11. Cheng Y^#, Wang ZM^#, Tan W^#, Wang X^#, Li Y, Bai B, Li Y, Zhang SF, Yan HL, Chen ZL, Liu CM, Mi TW, Xia S, Zhou Z, Liu A, Tang GB, Liu C, Dai ZJ, Wang YY, Wang H, Wang X, Kang Y, Lin L, Chen Z, Xie N, Sun Q, Xie W, Peng J, Chen D*, Teng ZQ*, Jin P*. Partial loss of psychiatric risk gene Mir137 in mice causes repetitive behavior and impairs sociability and learning via increased Pde10a. Nature Neuroscience 2018, 21(12): 1689-1703.
12. Duan RS^#, Tang GB^#, Du HZ^#, Hu YW, Liu PP, Xu YJ, Zeng YQ, Zhang SF, Wang RY, Teng ZQ, Liu CM*. Polycomb protein family member CBX7 regulates intrinsic axon growth and regeneration. Cell Death and Differentiation 2018, 25(9): 1598-1611.
13. Liu PP, Xu YJ, Teng ZQ, Liu CM*. Polycomb Repressive Complex 2: Emerging Roles in the Central Nervous System. Neuroscientist 2018, 24(3): 208-220.
14. Liu PP, Tang GB, Xu YJ, Zeng YQ, Zhang SF, Du HZ, Teng ZQ*, Liu CM*. MiR-203 Interplays with Polycomb Repressive Complexes to Regulate the Proliferation of Neural Stem/Progenitor Cells. Stem Cell Reports 2017, 9(1): 190-202.
15. Chen R^#, Zhang J^#, Fan N^#, Teng ZQ^#, Wu Y^#, Yang H, Tang YP, Sun H, Song Y, Chen C*. Δ9-THC-caused synaptic and memory impairments are mediated through COX-2 signaling. Cell 2013, 155(5): 1154-1165.
16. Liu C^#, Teng ZQ^#, Santistevan NJ, Szulwach KE, Guo W, Jin P, Zhao X*. Epigenetic regulation of miR-184 by MBD1 governs neural stem cell proliferation and differentiation. Cell Stem Cell 2010, 6(5): 433-44.

专利情况：

1. 发明名称：一种高效感染原代小胶质细胞的重组突变腺相关病毒及其相关生物材料。发明人：滕兆乾；何炫程；刘长梅；杜洪震。专利号：ZL 2021 1 0021870.7。授权公告日：2022年05月10日。
2. 发明名称：一种多能干细胞诱导产生小胶质细胞的方法及试剂盒。发明人：滕兆乾；李骞；刘长梅；杜洪震。专利号：ZL 2019 1 0558177.6。授权公告日：2021年10月29日。