姓 名: |
顾 奇 |
学 科: |
生物医学工程 |
电话/传真: |
+86-10-64807315 / |
电子邮件: |
qguATioz.ac.cn |
通讯地址: |
北京市朝阳区北辰西路1号院5号 100101 |
更多信息: |
生物制造研究组
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简历介绍:
顾奇,博士生导师,中国科学院动物研究所研究员,北京干细胞与再生医学研究院双聘研究员。致力于干细胞特异材料及3D打印平台开发;结合多技术体系再造复杂组织器官功能系统。主持多项科研项目,包括中国科学院A类先导“器官重建与制造”中生物墨水和打印装置方向负责人,科技部战略性国际科技创新合作重点专项负责人,中国科学院院装备项目负责人等。获中国科学院相关人才计划(结题优秀)、基金委优青资助,当选2022年中国干细胞学会卓越青年研究员,获2023年澳中科学研发杰出校友奖等。担任Biofabrication, Bioactive Materials, BMEMat, Cell Proliferation等杂志编委,以及中国生物材料学会先进制造分会等学会委员。
研究领域:
社会任职:
Biofabrication (IF=8.2) 编委
Bioactive Materials (IF=16.8) 青年编委
Cell Proliferation (IF=8.75) 编委
获奖及荣誉:
2023年 澳中科学研发杰出校友奖
2022年 国家自然科学基金委优秀青年基金(交叉学部)
2022年 中国干细胞协会卓越青年研究员
2017年 国家优秀自费留学生
2017年 伍伦贡大学优秀毕业论文
承担科研项目情况:
2022-2025,国家自然科学基金委区域创新发展联合基金,骨干,在研
2020-2023,中国科学院相关人才计划青年才俊择优支持项目(结题优秀),主持,结题
2017-2022,中国科学院A类先导专项“器官重建与制造” “功能性生物打印‘墨水’及个性化生物3D打印装置研发”项目,方向负责人,结题
2019-2023,战略性国际科技创新合作重点专项,首席,结题
2020-2022,中国科学院院级科研仪器设备研制项目,首席,在研
代表论著:
(*共同一作,#共同通信)
- Liu,X.,Li,J.,Zhu,L.,Huang,J.,Zhang,Q.,Wang,J.,Xie,J.,Dong,Q.,Zou,Z.,Huang,G. Gu,Q.#,Wang,J.# & Li,J.# (2024). Mechanistic insights into zinc oxide nanoparticles induced embryotoxicity via H3K9me3 modulation. Biomaterials,311,p.122679.
- Gao,Z.*,Ding,S.*,Fan,T.,Huang,W.,Zhao,X.,Liu,X.,Liu,W.,Zhang,M.# & Gu,Q.#,(2024). Protocol for embedded 3D printing of heart tissues using thiol-norbornene collagen. STAR protocols,5(2),p.102994.
- Sun,Y.,Ding,S.L.,Zhao,X.,Sun,D.,Yang,Y.,Chen,M.,Zhu,C.,Jiang,B.,Gu,Q.#,Liu,H.#and Zhang,M.#,2024. Self‐reinforced MOF‐based Nanogel Alleviates Osteoarthritis by Long‐acting Drug Release. Adv Mater,p.2401094.
- Wang,S.,Wang,X.,Jia,M.,Liu,W.,& Gu,Q. (2024). Thickening tissue by thinning electrospun scaffolds for skeletal muscle tissue engineering. BMEMat,e12084.
- An,J.,Zhang,S.,Chen,H.,Wu,J.,Xu,G.,Hou,Y.,Liu,R.,Li,N.,Cui,W.,Li,X.#,Du,Y.# and Gu,Q.#,(2024). Assessing bioartificial organ function: the 3P model framework and its validation. Lab on a Chip. 24,1586-1601
- An,J.*,Cui,W.*,Chen,H.*,Wu,J.,Liang,Y.,Li,N.,Du,Y.#,Zhang,S.# and Gu,Q.#,(2024). Manufacturing multi-organs database: A comprehensive,predictive,and analytical biofabrication database. International Journal of AI for Materials and Design,1(1),p.2420.
- Liu,Y.,Liu,X.#,Guo,H.,Wang,X.,Li,A.,Qiu,D.,& Gu,Q.# (2024). 3D bioprinting bioglass to construct vascularized full-thickness skin substitutes for wound healing. Materials Today Bio,24,100899.
- Zhang,S.*,Xu,G.*,Wu,J.*,Liu,X.,Fan,Y.,Chen,J.#,Wallace,G.,Gu,Q.#,(2023). Microphysiological constructs and systems: biofabrication tactics,biomimetic evaluation approaches,and biomedical applications. Small Methods,2300685.
- Gao,Z.*,Guo,J.*,Gou,B.*,Gu,Z.,Jia,T.,Ma,S.,Jia,T.,Ma,S.,Jiang,L.,Liu,W.,Zhou,L. and Gu,Q. (2023). Microcarriers promote the through interface movement of mouse trophoblast stem cells by regulating stiffness. Bioactive Materials,28,196-205. (Cover)
- Guo,B.,Duan,Y.,Li,Z.,Tian,Y.,Cheng,X.,Liang,C.,Liu,W.,An,B.,Wei,W.,Gao,T. and Liu,S.,Gu,Q.#,Zhou,Q.# and Wu,J.# (2023). High-Strength Cell Sheets and Vigorous Hydrogels from Mesenchymal Stem Cells Derived from Human Embryonic Stem Cells. ACS Applied Materials & Interfaces.
- Huang,W. H.*,Ding,S. L.*,Zhao,X. Y.,Li,K.,Guo,H. T.,Zhang,M. Z.#,& Gu,Q.# (2023). Collagen for neural tissue engineering: Materials,strategies,and challenges. Materials Today Bio,100639.
- Gao,T.*,Zhao,X.*,Hao,J.,Tian,Y.,Ma,H.,Liu,W.,...& Gu,Q.# (2023). A scalable culture system incorporating microcarrier for specialised mesenchymal stem cells from human embryonic stem cells. Materials Today Bio,100662.
- Ding,S.L*.,Zhao,X.Y*.,Xiong,W.,Ji,L.F.,Jia,M.X.,Liu,Y.Y.,Guo,H.T.,Qu,F.,Cui,W#.,Gu,Q#. and Zhang,M.Z#.,(2023). Cartilage Lacuna‐inspired Microcarriers Drive Hyaline Neocartilage Regeneration. Adv. Mater.,p.2212114. (Back cover)
- Gu,Z.*,Guo,J.*,Zhai,J.*,Feng,G.*,Wang,X.,Gao,Z.,Li,K.,Ji,S.,Wang,L.,Xu,Y.,Chen,X.,Wang,Y.,Guo,S.,Yang,M.,Li,L.,Han,H.,Jiang,L.,Wen,Y.,Wang,L.,Hao,J.,Li,W.,Wang,S.T.#,Wang,H.M.#,and Gu,Q.# (2022) A Uterus-inspired Niche Drives Blastocyst Development to the Early Organogenesis. Adv. Sci. (frontispiece)
- Liu,X.*,Wang,X.*,Zhang,L.*,Sun,L.*,Wang,H.,Zhao,H.,Zhang,Z.,Liu,W.,Huang,Y.,Ji,S.,Zhang,J.,Li,K.,Song,B.,Li,C.,Zhang,H.,Li,S.,Wang,S.#,Zheng,X.#,Gu,Q.#(2021) 3D Liver Tissue Model with Branched Vascular Networks by Multimaterial Bioprinting. Adv. Healthc. Mater.,2101405. (Cover)
- Fan,T.,Wang,S.,Jiang,Z.,Ji,S.,Cao,W.,Liu,W.,Ji,Y.,Li,Y.,Shyh-Chang,N. #,Gu,Q. #,(2021). Controllable assembly of skeletal muscle-like bundles through 3D bioprinting. Biofabrication,14(1),p.015009.
- Gu,Q.,Tomaskovic-Crook,E.,Lozano,R.,Chen,Y.,Kapsa,R.M.,Zhou,Q.,Wallace,G.G.#,and Crook,J.M.# (2016). Functional 3D Neural Mini-Tissues from Printed Gel-Based Bioink and Human Neural Stem Cells. Adv. Healthc. Mater. 5,1429-1438. (frontispiece)
- Gu,Q.,Tomaskovic-Crook,E.,Wallace,G.G.#,and Crook,J.M.# (2017).3D Bioprinting Human Induced Pluripotent Stem Cell Constructs For In Situ Cell Proliferation and Successive Multi-Lineage Differentiation. Adv. Healthc. Mater.,6(17),p.1700175. (Cover).
- Ding,S.L.,Liu,X.,Zhao,X.Y.,Wang,K.T.,Xiong,W.,Gao,Z.L.,Sun,C.Y.,Jia,M.X.,Li,C.,Gu,Q.#,Zhang,M.Z.#,(2022). Microcarriers in application for cartilage tissue engineering: Recent progress and challenges. Bioact. Mater.
- Zhao,H.,Huang,Y.,Lv,F.,Liu,L.,Gu,Q.#,Wang,S.# (2021) Biomimetic 4D-Printed Breathing Hydrogel Actuators by Nanothylakoid and Thermoresponsive Polymer Networks. Adv. Funct. Mater.,2105544.
- Li,X.*,Wang,Y.*,Ma,R.*,Liu,X.,Song,B.,Duan,Y.,Guo,J.,Feng,G.,Cui,T.,Wang,L.,Hao,J.#,Wang,H.M.#,Gu,Q.# (2021). Reconstruction of functional uterine tissues through recellularizing the decellularized rat uterine scaffolds by MSCs in vivo and in vitro. Biomed. Mater. 16 (3),035023.
- Zhao,H.,Xu,J.,Peng,K.,Fu,X.,Zhang,E.,Lv,F.,Liu,L.,Zhang,N.,Wang,Y.,Wang,S.#,Gu,Q.# (2020). Supramolecular Nanofibers for Encapsulation and In Situ Differentiation of Neural Stem Cells. Adv Healthc Mater,9 (1),1901295.
- Gu,Z.,Guo,J.,Wang,H.,Wen,Y.,and Gu,Q. (2020) Bioengineered microenvironment to culture early embryos. Cell Prolif 53,e12754.
- Sun,H.,Liu,J.,Li,S.,Zhou,L.,Wang,J.,Liu,L.,Lv,F.,Gu,Q#.,Wang,S#. (2019). Reactive Amphiphilic Conjugated Polymers for Inhibiting Amyloid β Assembly. Angew. Chem. Int. Ed 58,5988-5993.
- Gu,Q.,Tomaskovic-Crook,E.,Wallace,G.G.,and Crook,J.M. (2018) Engineering Human Neural Tissue by 3D Bioprinting,in Biomaterials for Tissue Engineering. Methods Mol. Biol. 1758: 129-138.
- Gu,Q.*,Hao,J.*,Lu,Y.,Wang,L.,Wallace,G. G.,& Zhou,Q. (2015). Three-Dimensional Bio-printing. Sci. China Life Sci. 58,411-419. (cover)
- Gu,Q.*,Zhu,H. ,Li,J.,Li,X.,Hao,J.,Wallace,G.G.,& Zhou,Q. (2016). Three Dimensional Bioprinting Speeds Up Smart Regenerative Medicine. Natl. Sci. 3 (3),331-344.
写给考生的话:
Free Your Mind. – Quote from “The Matrix” (1999)
博学之,审问之,慎思之,明辨之,笃行之。--《礼记·中庸》