姓  名: 顾 奇
学  科: 生物医学工程
电话/传真: +86-10-64807315 / 
电子邮件: qguATioz.ac.cn
通讯地址: 北京市朝阳区北辰西路1号院5号 100101
更多信息: 生物制造研究组     

简历介绍:

顾奇,博士生导师,中国科学院动物研究所研究员,北京干细胞与再生医学研究院双聘研究员。致力于干细胞特异材料及3D打印平台开发;结合多技术体系再造复杂组织器官功能系统。主持多项科研项目,包括中国科学院A类先导“器官重建与制造”中生物墨水和打印装置方向负责人,科技部战略性国际科技创新合作重点专项负责人,中国科学院院装备项目负责人等。获中国科学院相关人才计划(结题优秀)、基金委优青资助,当选2022年中国干细胞学会卓越青年研究员,获2023年澳中科学研发杰出校友奖等。担任Biofabrication, Bioactive Materials, BMEMat, Cell Proliferation等杂志编委,以及中国生物材料学会先进制造分会等学会委员。

研究领域:

生物材料与3D打印

社会任职:

Biofabrication (IF=8.2) 编委

Bioactive Materials (IF=16.8) 青年编委

Cell Proliferation (IF=8.75) 编委

获奖及荣誉:

2023年 澳中科学研发杰出校友奖

2022年 国家自然科学基金委优秀青年基金(交叉学部)

2022年 中国干细胞协会卓越青年研究员

2017年 国家优秀自费留学生

2017年 伍伦贡大学优秀毕业论文

承担科研项目情况:

2022-2025,国家自然科学基金委区域创新发展联合基金,骨干,在研

2020-2023,中国科学院相关人才计划青年才俊择优支持项目(结题优秀),主持,结题

2017-2022,中国科学院A类先导专项“器官重建与制造” “功能性生物打印‘墨水’及个性化生物3D打印装置研发”项目,方向负责人,结题

2019-2023,战略性国际科技创新合作重点专项,首席,结题

2020-2022,中国科学院院级科研仪器设备研制项目,首席,在研

代表论著:

(*共同一作,#共同通信)

  1. Liu,X.,Li,J.,Zhu,L.,Huang,J.,Zhang,Q.,Wang,J.,Xie,J.,Dong,Q.,Zou,Z.,Huang,G. Gu,Q.#,Wang,J.# & Li,J.# (2024). Mechanistic insights into zinc oxide nanoparticles induced embryotoxicity via H3K9me3 modulation. Biomaterials,311,p.122679.
  2. Gao,Z.*,Ding,S.*,Fan,T.,Huang,W.,Zhao,X.,Liu,X.,Liu,W.,Zhang,M.# & Gu,Q.#,(2024). Protocol for embedded 3D printing of heart tissues using thiol-norbornene collagen. STAR protocols,5(2),p.102994.
  3. Sun,Y.,Ding,S.L.,Zhao,X.,Sun,D.,Yang,Y.,Chen,M.,Zhu,C.,Jiang,B.,Gu,Q.#,Liu,H.#and Zhang,M.#,2024. Self‐reinforced MOF‐based Nanogel Alleviates Osteoarthritis by Long‐acting Drug Release. Adv Mater,p.2401094.
  4. Wang,S.,Wang,X.,Jia,M.,Liu,W.,& Gu,Q. (2024). Thickening tissue by thinning electrospun scaffolds for skeletal muscle tissue engineering. BMEMat,e12084.
  5. An,J.,Zhang,S.,Chen,H.,Wu,J.,Xu,G.,Hou,Y.,Liu,R.,Li,N.,Cui,W.,Li,X.#,Du,Y.# and Gu,Q.#,(2024). Assessing bioartificial organ function: the 3P model framework and its validation. Lab on a Chip. 24,1586-1601
  6. An,J.*,Cui,W.*,Chen,H.*,Wu,J.,Liang,Y.,Li,N.,Du,Y.#,Zhang,S.# and Gu,Q.#,(2024). Manufacturing multi-organs database: A comprehensive,predictive,and analytical biofabrication database. International Journal of AI for Materials and Design,1(1),p.2420.
  7. Liu,Y.,Liu,X.#,Guo,H.,Wang,X.,Li,A.,Qiu,D.,& Gu,Q.# (2024). 3D bioprinting bioglass to construct vascularized full-thickness skin substitutes for wound healing. Materials Today Bio,24,100899.
  8. Zhang,S.*,Xu,G.*,Wu,J.*,Liu,X.,Fan,Y.,Chen,J.#,Wallace,G.,Gu,Q.#,(2023). Microphysiological constructs and systems: biofabrication tactics,biomimetic evaluation approaches,and biomedical applications. Small Methods,2300685.
  9. Gao,Z.*,Guo,J.*,Gou,B.*,Gu,Z.,Jia,T.,Ma,S.,Jia,T.,Ma,S.,Jiang,L.,Liu,W.,Zhou,L. and Gu,Q. (2023). Microcarriers promote the through interface movement of mouse trophoblast stem cells by regulating stiffness. Bioactive Materials,28,196-205. (Cover)
  10. Guo,B.,Duan,Y.,Li,Z.,Tian,Y.,Cheng,X.,Liang,C.,Liu,W.,An,B.,Wei,W.,Gao,T. and Liu,S.,Gu,Q.#,Zhou,Q.# and Wu,J.# (2023). High-Strength Cell Sheets and Vigorous Hydrogels from Mesenchymal Stem Cells Derived from Human Embryonic Stem Cells. ACS Applied Materials & Interfaces.
  11. Huang,W. H.*,Ding,S. L.*,Zhao,X. Y.,Li,K.,Guo,H. T.,Zhang,M. Z.#,& Gu,Q.# (2023). Collagen for neural tissue engineering: Materials,strategies,and challenges. Materials Today Bio,100639.
  12. Gao,T.*,Zhao,X.*,Hao,J.,Tian,Y.,Ma,H.,Liu,W.,...& Gu,Q.# (2023). A scalable culture system incorporating microcarrier for specialised mesenchymal stem cells from human embryonic stem cells. Materials Today Bio,100662.
  13. Ding,S.L*.,Zhao,X.Y*.,Xiong,W.,Ji,L.F.,Jia,M.X.,Liu,Y.Y.,Guo,H.T.,Qu,F.,Cui,W#.,Gu,Q#. and Zhang,M.Z#.,(2023). Cartilage Lacuna‐inspired Microcarriers Drive Hyaline Neocartilage Regeneration. Adv. Mater.,p.2212114. (Back cover)
  14. Gu,Z.*,Guo,J.*,Zhai,J.*,Feng,G.*,Wang,X.,Gao,Z.,Li,K.,Ji,S.,Wang,L.,Xu,Y.,Chen,X.,Wang,Y.,Guo,S.,Yang,M.,Li,L.,Han,H.,Jiang,L.,Wen,Y.,Wang,L.,Hao,J.,Li,W.,Wang,S.T.#,Wang,H.M.#,and Gu,Q.# (2022) A Uterus-inspired Niche Drives Blastocyst Development to the Early Organogenesis. Adv. Sci. (frontispiece)
  15. Liu,X.*,Wang,X.*,Zhang,L.*,Sun,L.*,Wang,H.,Zhao,H.,Zhang,Z.,Liu,W.,Huang,Y.,Ji,S.,Zhang,J.,Li,K.,Song,B.,Li,C.,Zhang,H.,Li,S.,Wang,S.#,Zheng,X.#,Gu,Q.#(2021) 3D Liver Tissue Model with Branched Vascular Networks by Multimaterial Bioprinting. Adv. Healthc. Mater.,2101405. (Cover)
  16. Fan,T.,Wang,S.,Jiang,Z.,Ji,S.,Cao,W.,Liu,W.,Ji,Y.,Li,Y.,Shyh-Chang,N. #,Gu,Q. #,(2021). Controllable assembly of skeletal muscle-like bundles through 3D bioprinting. Biofabrication,14(1),p.015009.
  17. Gu,Q.,Tomaskovic-Crook,E.,Lozano,R.,Chen,Y.,Kapsa,R.M.,Zhou,Q.,Wallace,G.G.#,and Crook,J.M.# (2016). Functional 3D Neural Mini-Tissues from Printed Gel-Based Bioink and Human Neural Stem Cells. Adv. Healthc. Mater. 5,1429-1438. (frontispiece)
  18. Gu,Q.,Tomaskovic-Crook,E.,Wallace,G.G.#,and Crook,J.M.# (2017).3D Bioprinting Human Induced Pluripotent Stem Cell Constructs For In Situ Cell Proliferation and Successive Multi-Lineage Differentiation. Adv. Healthc. Mater.,6(17),p.1700175. (Cover).
  19. Ding,S.L.,Liu,X.,Zhao,X.Y.,Wang,K.T.,Xiong,W.,Gao,Z.L.,Sun,C.Y.,Jia,M.X.,Li,C.,Gu,Q.#,Zhang,M.Z.#,(2022). Microcarriers in application for cartilage tissue engineering: Recent progress and challenges. Bioact. Mater.
  20. Zhao,H.,Huang,Y.,Lv,F.,Liu,L.,Gu,Q.#,Wang,S.# (2021) Biomimetic 4D-Printed Breathing Hydrogel Actuators by Nanothylakoid and Thermoresponsive Polymer Networks. Adv. Funct. Mater.,2105544.
  21. Li,X.*,Wang,Y.*,Ma,R.*,Liu,X.,Song,B.,Duan,Y.,Guo,J.,Feng,G.,Cui,T.,Wang,L.,Hao,J.#,Wang,H.M.#,Gu,Q.# (2021). Reconstruction of functional uterine tissues through recellularizing the decellularized rat uterine scaffolds by MSCs in vivo and in vitro. Biomed. Mater. 16 (3),035023.
  22. Zhao,H.,Xu,J.,Peng,K.,Fu,X.,Zhang,E.,Lv,F.,Liu,L.,Zhang,N.,Wang,Y.,Wang,S.#,Gu,Q.# (2020). Supramolecular Nanofibers for Encapsulation and In Situ Differentiation of Neural Stem Cells. Adv Healthc Mater,9 (1),1901295.
  23. Gu,Z.,Guo,J.,Wang,H.,Wen,Y.,and Gu,Q. (2020) Bioengineered microenvironment to culture early embryos. Cell Prolif 53,e12754.
  24. Sun,H.,Liu,J.,Li,S.,Zhou,L.,Wang,J.,Liu,L.,Lv,F.,Gu,Q#.,Wang,S#. (2019). Reactive Amphiphilic Conjugated Polymers for Inhibiting Amyloid β Assembly. Angew. Chem. Int. Ed 58,5988-5993.
  25. Gu,Q.,Tomaskovic-Crook,E.,Wallace,G.G.,and Crook,J.M. (2018) Engineering Human Neural Tissue by 3D Bioprinting,in Biomaterials for Tissue Engineering. Methods Mol. Biol. 1758: 129-138.
  26. Gu,Q.*,Hao,J.*,Lu,Y.,Wang,L.,Wallace,G. G.,& Zhou,Q. (2015). Three-Dimensional Bio-printing. Sci. China Life Sci. 58,411-419. (cover)
  27. Gu,Q.*,Zhu,H. ,Li,J.,Li,X.,Hao,J.,Wallace,G.G.,& Zhou,Q. (2016). Three Dimensional Bioprinting Speeds Up Smart Regenerative Medicine. Natl. Sci. 3 (3),331-344.

写给考生的话:

  Free Your Mind.  – Quote from “The Matrix” (1999)

  博学之,审问之,慎思之,明辨之,笃行之。--《礼记·中庸》

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