季芬，女，博士，副研究员，干细胞与生殖生物学国家重点实验室神经干细胞增殖与分化研究组成员。2008年毕业于中科院北京基因组研究所，获理学博士学位，师从曾长青研究员。2008年到2011年在中科院微生物研究所从事博士后研究，合作导师为田波院士。2011年11加入中科院动物研究所神经干细胞增殖与分化研究组任助理研究员。2019年7月晋升为副研究员。

　　脑发育过程中神经干细胞增殖与分化的分子调控机制。

• 　　国家自然科学青年基金项目（31300894），主持，2013-2016
• 　　国家重大科学研究计划（2014CB964600），科研骨干，2014-2018
• 　　国家重点研发计划项目（2019YFA0110300），科研骨干，2019-2023

1. Fen Ji; Wenwen Wang; Chao Feng; Fei Gao; Jianwei Jiao^*. Brain-specific Wt1 Deletion Leads to Depressive-like Behaviors in Mice via the Recruitment of Tet2 to Modulate Epo Expression. Molecular Psychiatry, 2020.
2. Feng Chao, Zhao Jinyue, Ji Fen, Su Libo, Chen Y, Jiao Jianwei*. TCF20 dysfunction leads to cortical neurogenesis defects and autistic-like behaviors in mice. EMBO Rep. 2020.
3. Huimin Qiao^#; Yanxin Li^#; Chao Feng; Shuguang Duo; Fen Ji^*; Jianwei Jiao^*. Nap1l1 Controls Embryonic Neural Progenitor Cell Proliferation and Differentiation in the Developing Brain. Cell Reports, 2018, 22: 2279-2293.
4. Tianjin Shen; Fen Ji; Yuanyuan Wang; Xuepei Lei; Dongming Zhang; Jianwei Jiao^*. Brain-specific deletion of histone variant H2A.z results in cortical neurogenesis defects and neurodevelopmental disorder. Nucleic Acids Research, 2018, 46(5): 2290-2307.
5. Ji, Fen^#; Shen, Tianjin^#; Zou, Wenzheng; Jiao, Jianwei^*. UCP2 Regulates Embryonic Neurogenesis via ROS-mediated Yap Alternation in the Developing Neocortex. Stem Cells, 2017, 35: 1479-1492.
6. Shukun Wang^#; Qingli Liang^#; Huimin Qiao; Hong Li; Tianjin Shen; Fen Ji; Jianwei Jiao^*. DISC1 Regulates Astrogenesis in the Embryonic Brain via Modulation of RAS/MEK/ERK Signaling Through RASSF7. Development, 2016, 143(15): 2732-2740.
7. Tianjin Shen^#; Fen Ji^#; Zengqiang Yuan; Jianwei Jiao^*. CHD2 is Required for Embryonic Neurogenesis in the Developing Cerebral Cortex. Stem cells, 2015, 33: 1794-1806.
8. Shen Tianjin; Ji Fen; Jiao Jianwei^*. Epigenetics: major regulators of embryonic neurogenesis. Science Bulletin, 2015, 60(20): 1734-1743.
9. Zhang Juan^#; Ji Fen^#; Liu Yanli; Lei Xuepei; Li Hong; Ji Guangju; Yuan Zengqiang; Jiao Jianwei^*. Ezh2 Regulates Adult Hippocampal Neurogenesis and Memory. Journal of Neuroscience, 2014, 34(15): 5184-5199.
10. Wang Shukun^#; Li Baoguo^#; Qiao Huimin; Lv Xiaohui; Liang Qingli; Shi Zixiao; Xia Wenlong; Ji Fen; Jiao Jianwei^*. Autophagy-related gene Atg5 is essential for astrocyte differentiation in the developing mouse cortex. EMBO Reports, 2014, 15(10): 1053-1061.
11. Ji Fen; Lv Xiaohui; Jiao Jianwei^*. The Role of microRNAs in Neural Stem Cells and Neurogenesis. Journal of Genetics and Genomics, 2013, 40(2): 61-66.
12. Ji Fen; Yang Bin; Peng Xiangxin; Ding Huiguo; You Hong; Tien Po*. Circulating microRNAs in hepatitis B virus-infected patients. Journal of Viral Hepatitis, 2011, 18(7): E242-E251.
13. Ji Fen; Zhou Li; Ma Sufang; Li Feifei; Ding Huiguo; Zeng Changqing*. Dynamic Changes of HBV Quasispecies and Deletion Patterns in a Chronic Hepatitis B Patient. Journal of Medical Virology, 2009, 81(9): 1551-1559.