马帅，北京干细胞与再生医学研究院“致一”研究员，中国科学院动物研究所副研究员，中国科学院干细胞与再生医学数据中心办公室副主任，中国科学院青促会会员。入选第七届中国科协“青年人才托举工程”。主要研究方向为系统衰老生物学研究，利用单细胞测序和基因编辑等技术开展系统水平衰老、衰老相关疾病以及衰老干预的新型分子机制的挖掘与解析。以第一/通讯（含共同）作者在Cell、Cell Stem Cell、Cell Research、Nature Cell Biology、PNAS、Nucleic Acids Research、Protein & Cell等杂志上发表多篇研究论文。基金委优秀青年项目负责人，科技部重点研发计划课题组长。代表性成果获2020年度“中国科学十大进展”及“中国生命科学十大进展” 、2020年度Cell Press最受欢迎中国论文奖。

　　教育背景及工作经历：

　　教育背景

　　2008.09 - 2012.07，河南师范大学，生命科学学院，生物科学专业，理学学士

　　2012.09 - 2018.07，中国科学院动物研究所，动物生态与保护生物学院重点实验室，

　　基因组学专业，理学博士。导师：魏辅文 院士

　　工作经历

　　2018.08 - 2020.01，中国科学院生物物理研究所，生物大分子国家重点实验室，助理研究员

　　2020.02 - 2021.07，中国科学院动物研究所，膜生物学国家重点实验室，助理研究员

　　2021.08 - 至今， 中国科学院动物研究所，膜生物学国家重点实验室，副研究员

　　2021.06 - 至今， 北京干细胞与再生医学研究院，“致一”研究员

　　2021.01 - 至今， 中国科学院干细胞与再生医学创新研究院，干细胞与再生医学数据中心， 办公室副主任

　　围绕机体系统衰老的生物学研究，通过啮齿类和灵长类研究模型体系，利用单细胞测序等技术，开展衰老、衰老相关疾病及其干预的新型分子机制的挖掘与解析。

　　基金委，优秀青年科学基金项目，项目负责人。项目时间：2024.01-2026.12

　　基金委，面上基金项目，项目负责人。项目时间：2023.01-2026.12

　　基金委，青年科学基金项目，项目负责人。项目时间：2021.01-2023.12

　　科技部，国家重点研发计划，课题组长。项目时间：2022.12-2027.11

　　科技部，国家重点研发计划，课题骨干。项目时间：2018.12-2022.12

1. Ma, S#., Sun, S#., Geng, L#., Song, M#., Wang, W., Ye, Y., Ji, Q., Zou, Z., Wang, S., He, X., Li, W., Rodriguez Esteban C, Long, X., Guo, G., Chan, P., Zhou, Q., Belmonte JC*., Zhang, W*., Qu, J*., Liu, GH*. (2020). Caloric Restriction Reprograms the Single-Cell Transcriptional Landscape of Rattus Norvegicus Aging. Cell, 180(5): 984-1001.
2. Ma, S#., Wang, S#., Ye, Y#., Ren, J#., Chen, R#., Li, W., Li, J., Zhao, L., Zhao, Q., Sun, G., Jing, Y., Zuo, Y., Xiong, M., Yang, Y., Wang, Q., Lei, J., Sun, S., Long, X., Song, M., Yu S., Chan, P., Wang, J., Zhou, Q., Belmonte JC., Qu, J*., Zhang, W*., Liu, GH*. (2022). Heterochronic parabiosis induces stem cell revitalization and systemic rejuvenation across aged tissues. Cell Stem Cell, 29(6): 990-1005. e10. 
3. Ma, S#., Sun, S#., Li, J#., Fan, Y#., Qu, J#., Sun, L#., Wang, S#., Zhang, Y., Yang, S., Liu, Z., Wu, Z., Zhang, S., Wang, Q., Zheng, A., Duo, S., Yu, Y., Belmonte JC., Chan, P., Zhou, Q., Song, M*., Zhang, W*., Liu, GH*. (2020). Single-cell transcriptomic atlas of primate cardiopulmonary aging. Cell Research, 31(4): 415-432.
4. Ma, S#., Wu, Q., Hu, YB*., Wei, FW. (2018). Patterns and effects of GC3 heterogeneity and parsimony informative sites on phylogenetic tree of genes. Gene, 655: 56-60.
5. Ma, S*#., Chi, X#, Cai, Y#, Ji, Z#, Wang, S*, Ren, J*, Liu, GH*. Decoding Aging Hallmarks at the Single-Cell Level. (2023). Annual Review of Biomedical Data Science. doi:10.1146/annurev-biodatasci-020722-120642.
6. Wang, S#., Yao, XH#., Ma, S#., Ping, YF#., Fan, YL#., Sun, SH#., He, ZC#., Shi, Y#., Sun, L#., Zhang, PP#., Song, M#., Cai, J., Li, JM., Tang, R., Zhao, LY., Wang, CF., Wang, QR., Zhao, L., Hu, HF., Liu, XD., Sun, GQ., Chen, L., Pan, GQ., Li, QR., Zhao, GG., Xu, YY., Yang, YG., Huang, XQ., Li, W., Liu, ZH., Wang, HM., Wu, HB., Hu, BY., Ren, Y., Zhou, Q., Qu, J*., Zhang, WQ*., Liu, GH*., Bian, XW*. (2021). A single-cell transcriptomic landscape of the lungs of patients with COVID-19. Nature Cell Biology, 23(12), 1314-1328.
7. Shuhui Sun#; Shuai Ma#; Yusheng Cai#; Si Wang#; Jie Ren#; Yuanhan Yang#; Jiale Ping; Xuebao Wang; Yiyuan Zhang; Haoteng Yan; Wei Li; Concepcion Rodriguez Esteban; Yan Yu;Feifei Liu; Juan Carlos Izpisua Belmonte; Weiqi Zhang*; Jing Qu*; Guang-Hui Liu*; A single-cell transcriptomic atlas of exercise-induced anti-inflammatory and geroprotective effects across the body, The Innovation, 2023, 5(1): 100380.
8. Yan, HT#., Wang, RH#., Ma, S#., Huang, DR#., Wang, S., Ren, J., Lu, CF., Chen, X., Lu, XY., Zheng, ZK., Zhang, WQ*., Qu, J*., Zhou, YC*., Liu, GH*. (2022). Lineage Landscape: a comprehensive database that records lineage commitment across species, Nucleic Acids Research (IF = 19.16), doi.org/10.1093/nar/gkac951.
9. Kang, W#., Jin, T#., Zhang, T#., Ma, S#., Yan, HT., Liu, ZP., Ji, ZJ., Cai, YS., Wang, S., Song, MS., Ren, J., Hu, BY., Zhou, Q., Zhang, WQ*., Qu, J*., Bao, YM*., Liu, GH*. (2021). Regeneration Roadmap: database resources for regenerative biology. Nucleic Acids Research (IF = 19.16), 50(D1): D1085-D1090.
10. Aging Atlas Consortium, Zhang, W*., Qu, J*., Bao, Y*., Liu, GH*. (2020). Aging Atlas: A Multi-Omics Database for Aging Biology. Nucleic Acids Research, 49(D1): D825-D830.
11. Hu, YB#., Wu, Q#., Ma, S#., Ma, TX#., Shan L., Wang, X., Nie, YG., Ning, ZM., Yan, L., Xiu, YF., Wei, FW*. (2017). Comparative genomics reveals convergent evolution between the bamboo-eating giant and red pandas. Proc. Natl. Acad. Sci, 114(5):1081-1086.
12. Zhang Y#, Zheng Y#, Wang S#, Fan Y, Ye Y, Jing Y, Liu Z, Yang S, Xiong M, Yang K, Hu J, Che S, Chu Q, Song M, Liu GH*, Zhang W*, Ma, S*., Jing Qu*. (2022). Single-nucleus transcriptomics reveals a gatekeeper role for FOXP1 in primate cardiac aging. Protein & Cell. 14(4): 279-293.
13. Lan-Zhu Li#; Kuan Yang#; Yaobin Jing#; Yanling Fan; Xiaoyu Jiang; Si Wang; Guang-Hui Liu*; Jing Qu*; Shuai Ma*; Weiqi Zhang*. (2023) CRISPR-based screening identifies XPO7 as apositive regulator of senescence, Protein & Cell, pwad012.
14. Chu, Q#., Liu, FF#., He, YF#., Jiang, XY., Cai, YS., Wu ZM., Yan, KW., Geng, LL., Zhang YC., Wang, S., Zhang, WQ., Liu, GH*., Ma, S*., Qu, J*., Song, MS*. (2021). mTORC2/RICTOR exerts differential levels of metabolic control in human embryonic, mesenchymal and neural stem cells. Protein & Cell, 13(9): 676-682.
15. Li H#., Zhu L#., Wang R#., Xie, LH#., Ren, Jie#., Ma, S#., Zhang, WQ#., Liu XX., Huang, ZH., Chen, BY., Li, ZH., Feng, HY., Liu, GH*., Wang, S*., Qu, J*., Su WR*. (2021). Aging weakens Th17 cell pathogenicity and ameliorates experimental autoimmune uveitis in mice. Protein & Cell, 13(6): 422-445.